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Cell Signaling Technology Inc
rabbit polyclonal anti α synuclein Rabbit Polyclonal Anti α Synuclein, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/mab+2628/pmc12997674-87-8-14?v=Cell+Signaling+Technology+Inc Average 95 stars, based on 1 article reviews
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Cell Signaling Technology Inc
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The Human Musashi 1 Antibody from R D Systems is a mouse monoclonal antibody to Musashi 1 This antibody reacts with human The Human Musashi 1 Antibody has been validated for the following applications Western
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The Human Musashi-1 Antibody from R&D Systems is a Musashi-1 antibody to Musashi-1. This antibody reacts with Human. The Musashi-1 antibody has been validated for the following applications: Western Blot.
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Image Search Results
Journal: Human molecular genetics
Article Title: TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains.
doi: 10.1093/hmg/ddq290
Figure Lengend Snippet: Figure 5. TRAF6 binds aSYN and enhances its ubiquitination with atypical chains. (A) HEK cells were transfected with FLAG–TRAF6 and MYC–aSYN wt or A53T (mut). Lysates were immunoprecipitated with anti-FLAG agarose beads and bound proteins were revealed with anti-MYC and anti-FLAG antibodies. Inputs were tested for the expression of TRAF6 and aSYN proteins. (B) Cells were transfected with HA–ubiquitin, MYC–aSYN (wt or A53T) and FLAG– TRAF6 (wt or DN). For in vivo ubiquitination assay, lysates were immunoprecipitated with anti-MYC antibody. Immunoprecipitates and lysates were analyzed with anti-MYC, anti-FLAG and anti-HA antibodies. (C) HA–ubiquitin mutants in which only the indicated lysine residue is available for chain formation were used. Wt and K0 ubiquitin were included as controls. In vivo ubiquitination of aSYN wt was performed as in (B).
Article Snippet: Mouse monoclonal (#2647) and
Techniques: Ubiquitin Proteomics, Transfection, Immunoprecipitation, Expressing, In Vivo, Residue
Journal: Human molecular genetics
Article Title: TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains.
doi: 10.1093/hmg/ddq290
Figure Lengend Snippet: Figure 6. TRAF6 colocalizes with aSYN in LBs and accumulates in PD post-mortem brains. (A) Cryo-sections of post-mortem brain tissues were taken from healthy individuals and endogenous TRAF6 was visualized by immunohistochemistry. DA neurons were identified with anti-TH antibody. (B) TRAF6 was ana- lyzed by immunohistochemistry in SN of PD patients. LBs were visualized with anti-aSYN antibody. (C) Total RNA was extracted from SN of six PD and three control brains. TRAF6 mRNA was measured by qPCR relative to b-actin. Significance between PD and control group was calculated with t-test.
Article Snippet: Mouse monoclonal (#2647) and
Techniques: Immunohistochemistry, Control